specific T cell reactivity
The ubiquitously distributed Epstein-Barr Virus (EBV) belongs to the familiy of Herpesviridae. The prevalence of infected adults ranges from 95-99% in industrial countries.
The virus life-long persists in several cell types after primary infection. Reactivation of an EBV-infection can occur not only in immunosuppressed or organ transplanted patients, but also in immunocompetent donors.
The AID EBVSpot EliSpot Assay detects and measures the Interferon-y expression of EBV-specific effector T cells.